Soft implantable bioelectronics create engineered interfaces that mechanically match cardiac tissues, enabling stable, low-impedance coupling with the beating heart. We design device architectures and
wireless system modules optimized for chronic cardiovascular use,
ensuring reliable operation under continuous dynamic deformation.
In detail, we developed high-efficiency wireless communication and
power-transfer technologies suitable for deep-tissue implantation (Nature Reviews Bioengineering, 2024; Science Advances, 2022),
enabling continuous monitoring of electrophysiological and
hemodynamic signals essential for detecting arrhythmia, ischemia,
and early heart-failure progression. We also engineered minimally
invasive sensors, soft stimulators, and compact RF-ablation tools to
reduce surgical burden and increase procedural precision in
interventional cardiology (Nature Communications, 2015; Advanced Materials, 2024). In addition, our conformal
multichannel epicardial electrode arrays provide high-resolution
conduction mapping and targeted modulation of arrhythmogenic
regions (Science Advances, 2023). Cell-sheet–based approaches
further offer complementary potential for cardiac tissue
regeneration (Nature Communications, 2019). Together, these
technologies establish a foundation for next-generation, closed-loop
cardiac bioelectronic systems for personalized cardiovascular
diagnostics and therapy.