Soft bioelectronics offer clinically meaningful solutions for neurological disease by enabling minimally invasive, localized, and programmable therapies. For example, we developed flexible, adhesive, and biodegradable wireless implants that deliver chemotherapeutics directly to brain-tumor sites, improving local efficacy while reducing systemic toxicity (^(M)Nature Communications, 2019). This approach was extended with injectable hydrogel nanocomposites that provide deep tissue penetration and sustained postsurgical drug release (^(ⅰ)ACS Nano, 2023). To support more precise interventions, we created bioresorbable microneedles–integrated bioelectronics for localized delivery of theranostic nanoparticles and chemical agents (^(ⅱ)Advanced Materials, 2021), as well as implantable drug-delivery modules that can be wirelessly controlled through a wearable power-transfer system (^(ⅲ)Science Advances, 2021) Beyond drug delivery, our soft, dynamically adaptable peripheral neural interfaces enable stable recording and stimulation during tissue movement, opening pathways for next-generation neuroprosthetics and neuromodulation therapies (^(ⅳ)Advanced Materials, 2025)